Isotretinoin has the trade names accutane and roaccutane. It is used to cure severe acne when other treatments have failed.
For information about the use of isotretinoin, it's side effects, and some personal experiences of it's use; I reccomend the Acne and Roaccutane website. This site also has a links page to other sites, should you require more information.
For a selection of other interesting sites on the net, why not try my own sites list.